Antetokounmpo won the award in a landslide, receiving 75 first-place votes from a panel of 100 sportswriters and broadcasters and earning 432 points total.
Los Angeles Lakers forward Anthony Davis came in second with 14 first-place votes (200 points) and Utah Jazz center Rudy Gobert, who won the award in each of the last two seasons, finished third with six first-place votes (187 points).
Antetokounmpo, 25, anchored the best defensive team in the league in the Bucks, averaging 13.6 rebounds, 1 block and 1 steal in 30.4 minutes per game.
According to Second Spectrum, the Bucks superstar held opponents to 36.3% shooting during the regular season when he was the closest defender. That is the lowest field goal percentage allowed by any player in a season since Second Spectrum started tracking the stat in 2013-14 (minimum 525 field goal attempts).
Antetokounmpo is also the presumptive favorite to win MVP again this year. Only Olajuwon (1993-94) and Jordan (1987-88) have won both the MVP and Defensive Player of the Year awards in the same season.
Defensive Player of the Year has only been awarded since the 1982-83 season.