Andy Farrell has handed winger James Lowe his Six Nations debut, picking him over Jordan Larmour, as he announced his team to face Wales in the Principality Stadium on Sunday on the Six Nations.
Johnny Sexton has recovered from an injury to captain the side in his 12th Six Nations tournament and will be joined in the half-backs by Conor Murray.
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Garry Ringrose makes his return to an Ireland jersey after breaking his jaw and being unable to compete in the Autumn Nations Cup and is partnered by Robbie Henshaw.
Leinster’s Hugo Keenan will line out at full-back with support from Keth Earls and Lowe on the wings.
Sunday will be Cian Healy’s 50th Six Nations appearance as he lines out in the front-row alongside Rob Herring and Andrew Porter.
Locks Tadhg Beirne and James Porter have been listed by Farrell and the back-row is made up of Peter O’Mahony, Josh van der Flier and CJ Stander.
Tadhg Furlong, who missed 11 months of rugby through injury, is listed on the bench.
Ireland team
Hugo Keenan, Keith Earls, Garry Ringrose, Robbie Henshaw, James Lowe, Jonathan Sexton (captain), Conor Murray, Cian Healy, Rob Herring, Andrew Porter, Tadhg Beirne, James Ryan, Peter O’Mahony, Josh van der Flier.
Replacements: Ronan Kelleher, Dave Kilcoyne, Tadhg Furlong, Iain Henderson, Will Connors, Jamison Gibson Park, Billy Burns, Jordan Larmour.